Lanktree M.B., et al. (2023). A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulation. Kidney Int., 104(6), 1170-1184.
Proteome-wide Mendelian randomization study investigating the impact of 1,161 plasma protein biomarkers on eGFR. Kestenbaum, B., … Lanktree, M.B., … (2023). Clonal hematopoiesis of indeterminate potential and kidney function decline in the general population. AJKD, 81(3), 329-335. Study reporting an association between CHIP and eGFR decline in 3 general population cohorts without known kidney disease. Fryml, E. & Lanktree, M.B. (2023). Sodium-glucose cotransporter-2 inhibitors in patients without diabetes. CMAJ, 195(17): E619. Review highlighting key clinical knowledge regarding the use of sodium-glucose transporters in patients without diabetes. Mohammadi-Shemirani, P., …Lanktree, M.B. (2022). ACLY and CKD: a Mendelian randomization analysis. Kidney Int. Rep., 7(7), 1673-1681. Mendelian randomization study demonstrating that genetically reduced ACLY expression was significantly associated with CKD but not eGFR or ACR. Vlasschaert, C., ... Lanktree, M.B. (2021). Preprint servers in kidney disease research: A rapid review. Clin. J. Am. Soc. Nephrol., 16(3), 479-486. Rapid review discussing benefits and drawbacks of preprint servers in kidney disease research. Lanktree, M.B., et al. (2021). Patients with protein-truncating PKD1 mutations and mild ADPKD. Clin. J. Am. Soc. Nephrol., 16(3), 374-383. Study revealing presence of mild disease in 18% of patients with the most severe ADPKD-inducing mutation class, PKD1. Vlasschaert, C. & Lanktree, M.B. (2020). Microscopic hematuria. CMAJ, 192(14): E370. Overview of microscopic hematuria diagnosis and evaluation. Lanktree, M.B., et al. (2020). Insights into autosomal dominant polycystic kidney disease from genetic studies. Clin. J. Am. Soc. Nephrol., CJN.02320220. Overview of current challenges and future directions in PKD1 mutation screening. Ting, D.K., ... Lanktree, M.B., ... (2020). Quality appraisal and assurance techniques for free open access medical education (FOAM) resources: A rapid review. Semin. Nephrol., 40(3), 309-319. Rapid review discussing quality assessment of free open access medical education resources. Harrison, T.G., ... Lanktree, M.B., ... (2020). Improving sexual function in people with chronic kidney disease: A narrative review of an unmet need in nephrology research. Canadian J. Kidney Health Dis., 7:2054358120952202. Narrative review analyzing current challenges and progress in management of sexual dysfunction secondary to chronic kidney disease. Lanktree, M.B., et al. (2019). Intrafamilial variability of ADPKD. Kidney360, 4(7), 995-1003. Genetic epidemiology study revealing the presence of extreme kidney disease discordance in at least 12% of families with ADPKD, regardless of the underlying mutated gene or mutation class. Lanktree, M.B., et al. (2018). Prevalence estimates of polycystic kidney and liver disease by population sequencing. J. Am. Soc. Nephrol., 29(10), 2593-2600. Study establishing prevalence estimates of ADPKD and ADPLD using two comprehensive population sequencing databases, gnomAD and BRAVO. Lanktree, M.B. & Chapman, A.B. (2017). New treatment paradigms for ADPKD: moving towards precision medicine. Nat. Rev. Nephrol., 13, 750-768. Review describing early intervention strategies to optimize treatment of ADPKD patients based on their specific presentations. |
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